Among the standout fixtures is Victor Osimhen’s Galatasaray hosting Juventus, while Real Madrid renew their rivalry with Benfica in a dramatic rematch.

The first legs kick off on February 17, 2026, with return fixtures scheduled for February 24–25. The eight winners will advance to join the top-seeded clubs in the round of 16.

Galatasaray vs Juventus

Osimhen has been Galatasaray’s talisman in Europe this season, contributing a significant share of their goals during the league phase. The Turkish champions will rely heavily on the Nigerian striker, particularly at Rams Park, where the home crowd is known for creating a fierce atmosphere.

Galatasaray are expected to deploy quick transitions and aggressive pressing to unsettle Juventus’ defensive structure.

Juventus, however, bring tactical discipline and knockout-stage experience. The Italian side will likely prioritize defensive solidity while looking to capitalize on counter-attacking opportunities.

Real Madrid vs Benfica: Revenge on the Line

This tie carries added drama following their recent league-phase encounter, where Benfica stunned Real Madrid 4–2 at home.

Benfica’s high-energy display pushed Madrid into the play-offs, and the Portuguese side will aim to replicate that fearless approach at the Estádio da Luz.

Real Madrid, 15-time European champions, enter the tie as favourites on paper due to their pedigree and squad depth. However, they will be motivated by a desire for redemption after the earlier defeat.

Benfica’s coach, José Mourinho, has already described Madrid as “wounded and dangerous,” warning that the Spanish giants will respond strongly.

The second leg at the Santiago Bernabéu could prove decisive if Benfica secure an advantage in Lisbon.

Other Key Fixtures

Elsewhere:

Borussia Dortmund face Atalanta in what promises to be an open and attacking contest.

AS Monaco take on domestic rivals Paris Saint-Germain in a high-stakes all-French showdown.